The mechanical stirred multi-stage bioreactor is a new type of bioreactor, and its material selection and manufacturing process fully comply with CGMP requirements. Provide an ideal physiological and physical environment for the production of recombinant protein drugs during the amplification process, to meet the requirements of strain growth, metabolism, drug synthesis, maintenance of biomechanical performance, mass transfer mixing, and spatial structure.

Application scope:

Widely used in pilot projects in the biotechnology industry, the production scale includes monoclonal antibodies, viral vaccines, interferons tPA、 All genetically engineered biological products used for E. coli expression, including interleukins, G-CSF, etc.

Advantages:

1. Tank bodies can be designed with different height to diameter ratios according to different product requirements.

2. Completely leak free device, eliminates cross contamination, meets CGMP requirements, runs smoothly, and has low noise.

3. Adopting German Borgmann mechanical double end seals and self-developed components by KENOD, completely replacing imported sterile seals.

4. The shaft and impeller are processed in a special integrated manner to ensure the balanced operation of the impeller at high speeds.

5. There are more than ten different engineering strains of bacteria available for selection in the mixing paddle.

6. The bioreactor maintains high consistency and productivity even after fermentation amplification, and the control system adopts a tunable PID control loop for fully automatic control.

Application scope：

Widely used in biological high-tech industrial pilot, the scale of production including monoclonal antibodies, virus vaccine, interferon, tPA and interleukin, G-CSF etc. all used for e. coli express product genetic engineering of biological products.

Advantages：

1. Tank requirements for different products can be designed with different aspect ratio of the tank.

2. Completely leak-free installations, eliminating cross-contamination, consistent with CGMP requirements, sterile and stable operation, low noise.

3. Adopted the German Burgmann mechanical double seal+KENOD develop their own components, completely replace imported sterile seal.

4. Axis impeller machining using the special one, to ensure the balance of the impeller at high speed operation .

5. Stir equipped with a dozen different engineering strains, with choices to be made.

6. Bioreactor in the fermentation amplification remained high after the consistency and productivity, control system can be tuned PID control loop automatic controled.